Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.
In the two years following the death of Elizabeth Keen, Raymond Reddington and the members of the FBI Task Force have disbanded with Reddington's whereabouts unknown. When one of their own is injured in the line of duty, however, the Task Force is drawn back together to bring down a conspiracy that could shatter global security.
A kidnapping poses a test for the capabilities of the Task Force as they contend with a mysterious pirating organization.
A new case involving stolen artifacts reunites Red with a former blacklister. Aram faces a difficult decision.
The Task Force races to locate a blacklister who uses any means necessary to return what has been unjustly stolen. Ressler asks Park for a favor. Cooper tries to piece together an event for which he has no memory.
Dembe's position as an FBI agent causes complications for Red as the Task Force handles a case involving military technology. Cooper and Park each find their personal lives increasingly complicated.
The Task Force investigates a therapist who may be the key to the resurgence of an organized crime family. Red conducts an investigation of his own.
In a series of flashbacks, Ressler recalls his actions in the aftermath of Elizabeth Keen's death.
The death of a professional tennis player leads the Task Force to a doctor who may be fixing the odds for a major sports betting syndicate. Red digs deeper into Dembe's betrayal. Ressler struggles with sobriety.
A spate of coordinated attacks on Red's lieutenants puts Dembe in imminent danger, prompting him to relive the events that led him to join the FBI two years earlier.
The task force's investigation into Arcane Wireless, an untraceable cellular network for criminals, leads to unexpected consequences. Red races against the clock to get a colleague out of trouble.
An investigation into the Conglomerate, a group of former government-sponsored assassins, becomes complicated when the Task Force learns one of their own may have ties to the group. Red digs deeper into the events leading up to Liz's death.
The Task Force pursues their latest target, the Chairman, who operates a dark web stock market trading shares of criminal organizations. Red takes extreme measures to locate a tracking device, which sends Ressler into a spiral. Cooper makes contact with his blackmailer.
The Task Force is led to an unusual suspect when the wealthy clients of an apparent escort service start turning up dead. Red and a friend attempt to recover an item after reuniting at a friend's memorial. Cooper heads to Atlanta to follow a lead on his blackmailer.
While searching for Sen. Panabaker's missing daughter-in-law, the Task Force learns there may be a larger pattern of abductions. Red continues piecing together the mystery behind Liz's death.
Tensions rise when Cooper’s search for his blackmailer overlaps with the Task Force’s latest Blacklist case.
Red chases a lead that could shed light on both Liz’s death and Cooper’s blackmailing. The Task Force experiences a major shakeup when one of their own is taken into custody.
When a member of The Task Force is captured by the leader of a cartel, they turn to Red for guidance. Red investigates a seemingly impossible heist.
Red questions the whereabouts of a former associate. The Task Force hunts down a criminal dealing in illegal psychedelics.
Feeling the weight of recent pressures, Aram turns to an unusual outlet for release.
In an effort to reveal his true enemy, Red turns to the Task Force to help ground a flying fortress bank.
Red and the Task Force spring into action after learning who betrayed them.
Red and Cooper square off with conflicting endgames for their mutual traitor. A major secret about the Task Force falls into the wrong hands.